Compulsory masking for those on Mars, the Moon, and surgery rooms is arguably reasonable. Masking in China and other areas polluted with smog is another arguably reasonable safeguard. 

But a jump to permanently veiling each human from a microbe-- how can the risk-benefit balance?  So much has been lost already.  Mandated masking has already increased concussions by inducing fainting spells, decreased human visibility and communication. (Masking is especially not recommended during exertion-- including exercize.) 

I would like to know how effective  compulsion has been against the wars on drugs and corruption, as that is an arguably more important way to preserve health and wealth.